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Abstract #0259

Exploiting radiogenomics data for personalised prediction of glioblastoma

Paul Blakeley1,2, Chia-Feng Lu2,3,4, Fei-Ting Hsu2,5, Li-Chun Hsieh2,5, Yu-Chieh Jill Kao2,3, Huai-Lu Chen1,2, Ping-Huei Tsai2,3,5, Hua-Shan Liu2,6, Gilbert Aaron Lee1,2, and Cheng-Yu Chen2,3,5

1Department of Medical Research, Taipei Medical University Hospital, Taipei, Taiwan, 2Translational Imaging Research Center, College of Medicine, Taipei Medical University, Taipei, Taiwan, 3Department of Radiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, 4Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, 5Department of Medical Imaging, Taipei Medical University Hospital, Taipei, Taiwan, 6School of Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan

The present study demonstrates the feasibility of machine learning in radiogenomics to predict patient outcome. The Random Forest Survival model is able to predict patient survival based on apparent diffusion coefficients or gene expression data without any prior knowledge.

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