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Abstract #0272

Evaluation of CSF Suppression Techniques for Intracranial Vessel Wall Imaging

Petrice M. Cogswell1, Jeroen C.W. Siero2,3, Guillaume Gilbert4, Taylor Davis1, Allison O. Scott1, Katie Lants1, Helen B. Mahany1, Jennifer M. Watchmaker1, Jeroen Hendrikse2, and Manus J. Donahue1

1Vanderbilt University Medical Center, Nashville, TN, United States, 2Radiology, University Medical Center Utrecht, Netherlands, 3Spinoza Center for Neuroimaging, Amsterdam, Netherlands, 4MR Clinical Science, Philips Healthcare Canada, Markham, Canada

This work compares vessel wall SNR and CSF suppression from multiple approaches to determine optimal imaging parameters for intracranial VWI at the clinically-available field strength of 3T. T1-weighted TSE acquisition using variable refocusing angle pulse-train and DANTE preparation provides for blood and CSF suppression while maintaining adequate vessel wall SNR. The use of a variable refocusing pulse train with sweep of 40-120° provides improved performance compared to a sweep of 50-120°. Variation of the DANTE flip angle showed that a flip angle of 8° provides good CSF suppression with minimal SNR loss compared to flip angles of 10 and 12°.

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