Abstract #0293

Increased aortic wall shear stress and wall shear stress gradient in patients with an anatomically shaped sinus prosthesis using 4D Flow MRI

Victoria Schultz¹, Thekla Oechtering¹, Malte Sieren¹, Michael Scharfschwerdt², Anja Hennemuth³, Markus Hüllebrand³, Hans-Hinrich Sievers², Jörg Barkhausen¹, and Alex Frydrychowicz¹

¹Clinic for Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein, Lübeck, Germany, ²Department of Cardiac and Cardiothoracic Vascular Surgery, University Hospital Schleswig-Holstein, Lübeck, Germany, ³Mevis, Fraunhofer, Bremen, Germany

Patients with anatomically shaped sinus prosthesis have been shown to have near physiological hemodynamics in the aortic bulb but altered flow characteristics distal to the prosthesis. The aim of this study was to compare the aortic wall shear of 12 patients with sinus prosthesis with 12 age-matched volunteers using 4D flow sensitive MRI. The wall shear stress analysis in 8 analysis planes revealed a tendency towards decreased WSS in the region of the prosthesis and increased WSS values distal to the prosthesis. Interestingly, the WSS gradient per plane and segmental WSS distal to the prosthesis were increased throughout the patients.

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