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Abstract #0323

Insulinoma localization with cross-sectional imaging: head-to-head comparison of contrast-enhanced CT, volume perfusion CT and multi-parametric MR

Liang Zhu1, Zhao-yong Sun1, Hua-dan Xue1, Tian-yi Qian2, and Zheng-yu Jin1

1Radiology, Peking Union Medical College Hospital, Beijing, People's Republic of China, 2MR collaborations NE Asia, Siemens Healthcare, Beijing, People's Republic of China

This study aims to compare insulinoma localization with CECT, VPCT and multi-parametric MR (mp-MR) at 3T in the same patients, in a prospective manner. CECT, VPCT and mp-MR were performed in patients with suspected insulinomas. The presence/absence of tumor within the pancreatic head, neck, body and tail region was evaluated with 5-scale confidence levels. ROC analysis was performed. Surgical pathology served as reference standard. We found that VPCT and mp-MR showed improved diagnostic performance for insulinoma localization, compared to CECT. Both modalities could serve as problem-solving tools in difficult cases. mp-MR has the potential to replace CECT as the first-line examination.

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