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Abstract #0340

Association between Carotid Atherosclerotic Plaque Calcification and Intraplaque Hemorrhage: A High Resolution Magnetic Resonance Imaging Study

Shuo Chen1, Ruolan Lin2, Gaifen Liu3, Rui Li1, Yunjing Xue2, and Xihai Zhao1

1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, People's Republic of China, 2Department of Radiology, Fujian Union Hospital, People's Republic of China, 3Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, People's Republic of China

Carotid intraplaque hemorrhage (IPH) is associated with cardiovascular events. Calcification, frequently accompanied with IPH, may play a role in occurrence of IPH. In this study we aimed to investigate the associations between calcification characteristics and IPH in carotid plaques. Our results suggest that surface calcification and multiple calcification in carotid atherosclerotic plaques are independently associated with presence IPH. Both quantity and location of calcification may play important roles in occurrence of IPH. These findings may provide novel insights for understanding the mechanism of IPH.

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