Abstract #0357

Measuring Blood Oxygenation and Hematocrit with a Combined T2 and T1 Approach: Initial Experience in Humans

Thomas Christen¹, Jia Guo¹, Wendy Wei Ni¹, Michael Moseley¹, and Greg Zaharchuk¹

¹Radiology, Stanford University, Palo Alto, CA, United States

In this study, we propose to obtain simultaneous measurements of blood oxygen saturation (SO₂) and hematocrit (Hct) by combining two or more in vivo measurements of blood MR relaxation times. We tested our approach in 5 healthy human subjects using T2+T1 values and calibration curves obtained in vitro. The results found in the superior sagittal sinus vein (SO₂=62±5% and Hct=46±1%) are in good agreement with literature values and suggest great potential of the approach once it is further validated.

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