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Abstract #0368

Bayesian prediction for insufficient liver enhancement in gadoxetic acid-enhanced hepatobiliary phase imaging

Yuki Mori1, Utaroh Motosugi1, Tatsuya Shimizu1, Shintaro Ichikawa1, and Hiroshi Onishi1

1Department of Radiology, University of Yamanashi, Chuo, Japan

Insufficient liver enhancement due to decreased liver function is a major limitation in gadoxetic acid-enhanced hepatobiliary phase imaging (HBP). Recent research shows that insufficient liver enhancement is associated with liver function tests including total bilirubin level, Child-Pugh classifications, indocyanine green tests, and liver stiffness measured by MR elastography. However, none of these tests have been practically used for determining the patients with insufficient liver enhancement before MR imaging. We used univariate tests and logistic regression to determine predictive factors and performed cross validation to reveal utility of Bayesian method for predicting patients with insufficient liver enhancement in gadoxetic acid-enhanced HBP.

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