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Abstract #0467

Larmor frequency shift in anisotropic heterogeneous media

Alexander Ruh1,2 and Valerij G. Kiselev1,2

1Dept. of Radiology, Medical Physics, Medical Center - University of Freiburg, Freiburg, Germany, 2Faculty of Medicine, University of Freiburg, Freiburg, Germany

The question about the precise value of the proton Larmor frequency in neuronal tissues is a major topic in current research. In this study we present a comprehensive answer for spins moving in magnetically heterogeneous media formed by impermeable susceptibility inclusions. We obtain an analytic result for the mean Larmor frequency in the limit of fast diffusing spins in the space external to the inclusions. This mean frequency explicitly depends on the correlation function of the inclusion. For anisotropic media this results in a nonzero frequency shift, which is confirmed by Monte Carlo simulations.

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