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Abstract #0495

Fast quantitative 31P MRI using prior information from 1H MRI

Kristian Rink1, Nicolas G.R. Behl1, Christine Gnahm1, Peter Bachert1, and Armin M. Nagel1,2

1German Cancer Research Center (DKFZ), Heidelberg, Germany, 2University Hospital Erlangen, Erlangen, Germany

Phosphorus-containing biomolecules play a crucial role in the energy metabolism of the human body. Compared to hydrogen, the in vivo phosphorus MR signal is four orders of magnitude lower. In this study, a conventional gridding reconstruction applied on the phosphocreatine signal of the human calf was compared to a constraint iterative approach, which uses prior knowledge from hydrogen MRI data. For both reconstructions, different acquisition times were tested and phosphocreatine concentrations in the gastrocnemius and soleus muscles were estimated.

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