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Abstract #0523

Minimum peak power root-flipped gSlider-SMS RF pulses for high-resolution in vivo diffusion imaging

Jun Ma1, Thomas Witzel2, William A Grissom1, and Kawin Setsompop2

1Biomedical Engineering, Vanderbilt University, Nashville, TN, United States, 2Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States

gSlider is an RF encoding method that increases SNR in high-resolution diffusion imaging, by repeatedly acquiring high-SNR thick-slab images with distinct through-slice RF phase encoding. The method is currently based on linear-phase RF pulses designed using the inverse scattering transform. However, the high peak power of the associated refocusing pulses requires VERSE to meet practical peak RF amplitude constraints. Here we show that the pulses can be equivalently designed using the SLR algorithm, and that the refocusing pulse can be further root-flipped to minimize its peak amplitude and obviate the use of VERSE, while preserving gSlider encoding and linear-phase spin echoes.

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