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Abstract #0524

3D Multi-band Interleaved DW-EPI with 3D Phase Correction

Hing-Chiu Chang1, Edward S. Hui1,2, Xiaoxi Liu1, and Nan-kuei Chen3,4

1Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong, Hong Kong, 2The State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong, 3Department of Biomedical Engineering, University of Arizona, Tucson, AZ, United States, 4Brain Imaging and Analysis Center, Duke University Medical Center, Durham, NC, United States

The optimal SNR efficiency of 3D multi-slab multi-shot DWI acquisition can be enabled by using a TR range of 1-2s. However, due to the low feasible slab thickness, the multi-slab acquisition can only achieve limited brain coverage when using a short TR. In this study, we first develop a 3D multi-band (MB) iDW-EPI sequence with MB-EVI-based navigator to increase brain coverage when using optimal TR. Second, we extend 3D-MUSER algorithm, which is proposed in another study, to reconstruct 3D-MB-iDW-EPI data with 3D phase correction. Our preliminary result demonstrates the feasibility of 3D MB DWI with 3D phase correction.

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