Abstract #0532

Combined Late Gadolinium Enhancement (LGE) and 18F-fluorodeoxyglucose (18F-FDG) Uptake in a Hybrid PET/MR System to Diagnose Active Cardiac Sarcoidosis

Philip M Robson¹, Maria Giovanna Trivieri², Ronan Abgral³, Marc R Dweck⁴, Nicolas A Karakatsanis¹, Venkatesh Mani¹, Maria M Padilla⁵, Marc M Miller⁶, Anarahda Lala⁶, Javier Sanz⁶, Jagat Narula⁶, Valentin Fuster⁶, Johanna Contreras⁶, Jason Kovacic⁶, and Zahi A Fayad¹

¹Translational and Molecular Imaging Institute, icahn school of medicine at mount sinai, New York, NY, United States, ²icahn school of medicine at mount sinai, New York, NY, United States, ³Department of Nuclear Medicine, European University of Brittany, ⁴British Heart Foundation/University Centre for Cardiovascular Science, University of Edinburgh, ⁵Division of Pulmonary, Critical Care and Sleep Medicine, icahn school of medicine at mount sinai, New York, NY, United States, ⁶Cardiovascular Institute, icahn school of medicine at mount sinai, New York, NY, United States

Recent advances in hybrid Positron Emission Tomography (PET) Magnetic Resonance (MR) technology have enabled simultaneous imaging with both modalities. Sarcoidosis is a granulomatous disease that, when involving the heart has a poor prognosis. However, cardiac sarcoidosis has been shown to respond to immunosuppressive therapy. Currently, both late gadolinium enhancement (LGE)-MR and 18F-fluorodeoxyglucose (18F-FDG)-PET are used separately to evaluate the disease yet a clear diagnosis is not easily achieved. In this work, we investigate the potential improvement in evaluation with combined 18F-FDG-PET/MR imaging.

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