Meeting Banner
Abstract #0551

Cardiac Magnetic Resonance Elastography for Quantitative Assessment of Elevated Myocardial Stiffness in Cardiac Amyloidosis

Arvin Arani1, Shivaram P. Arunachalam1, Ian CY Chang2, Francis Baffour1, Kevin J Glaser1, Joshua D Trzasko1, Kiaran McGee1, Armando Manduca1, Martha Grogan2, Angela Dispenzieri3,4, Richard L Ehman1, and Philip A Araoz1

1Radiology, Mayo Clinic, Rochester, MN, United States, 2Cardiovascular Diseases, Mayo Clinic, Rochester, MN, United States, 3Medicine: Division of Hematology, Mayo Clinic, Rochester, MN, United States, 4Laboratory Medicine and Pathology, Mayo Clinic

Myocardial stiffness plays an important role in cardiac function. The objective of this study is to evaluate if 3D high frequency cardiac MR elastography (MRE) can measure increased myocardial stiffness in cardiac amyloidosis patients compared to healthy volunteers. Twenty-two patients with cardiac amyloidosis and 16 healthy volunteers were enrolled. The myocardial stiffness of cardiac amyloid patients (median: 11.4 kPa, min: 9.2, max: 15.7) was found to be significantly stiffer (p < 0.01) than healthy controls (median: 8.2 kPa, min: 7.2, max: 11.8). These results motivate future investigation of 3D high frequency cardiac MRE in different patient cohorts.

This abstract and the presentation materials are available to members only; a login is required.

Join Here