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Abstract #0629

Optimization of mpMRI protocol in differentiating muscle-invasive from non-muscle invasive Bladder Cancer:  is there room for Diffusion Tensor Imaging (DTI)?

Giovanni Barchetti1, Marcello Grompone1, Maurizio Del Monte1, Davide Carano1, Carlo Catalano1, and Valeria Panebianco1

1Department of Radiological Sciences, Sapienza University of Rome, Rome, Italy

Staging of BCa is critical, especially in differentiating non-invasive from muscle infiltrative lesions, as patient management strongly differs according to stage. Currently, patients with bladder lesions undergo two invasive procedures to diagnose and eventually treat the tumor if it is superficial. In this study we showed that mp-MRI has high capability for differentiating superficial from deep lesions, thanks also to DTI ability to directly visualize detrusor muscle layers. Mp-MRI could therefore be included systematically in the diagnostic evaluation of patients with suspicious bladder lesions in order to possibly avoid the first diagnostic cystoscopy once detrusor muscle invasion has been excluded.

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