Meeting Banner
Abstract #0636

Using transient intrinsic torsional shear wave propagation to measure Left Ventricular Myocardial stiffness with a 2D pencil beam navigator at 0.5ms temporal resolution: Initial results from phantom studies and volunteers

Jessica Webb1,2, Jurgen Runge1,3, Jordi Martorell4, Gerald Carr-White1,2, Reza Razavi1,2, David Nordsletten1, and Ralph Sinkus1

1Imaging Sciences & Biomedical Engineering, King's College London, London, United Kingdom, 2Department of Cardiology, Guys and St Thomas' NHS Trust, London, United Kingdom, 3Department of Radiology, Academic Medical Center, Amsterdam, Netherlands, 4Department of Chemical Engineering, Universitat Ramon Llull, Barcelona, Spain

Heart Failure with preserved Ejection Fraction is common, associated with high morbidity and mortality, and is challenging to diagnose. We have developed a novel patient friendly non-invasive technique to quantify myocardial stiffness using transient MR Elastography. Aortic valve closure results in a shear wave propagating through the myocardium. The torsional wave propagation can be visualised using a 2D pencil beam navigator positioned along the myocardium, using four breath holds each 15 seconds. With a temporal resolution of 0.5ms this technique can be used in all patients in sinus rhythm. Increased myocardial stiffness results in increased speed of shear wave propagation.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords