Abstract #0646

Anterior Tibial Translation Following ACL Reconstruction is Associated with Postsurgical Cartilage Matrix Changes.

Alan K Li¹, Valentina Pedoia ², Keiko Amano², Jonathan Ochoa², Qi Li ², Benjamin Ma², and Xiaojuan Li²

¹University of California, Berkeley, Berkeley, CA, United States, ²University of California, San Francisco, San Francisco, CA, United States

Biomechanical abnormalities and accelerated cartilage matrix changes are commonly seen following ACL injury; however, the association between the two remains unclear. The purpose of this study was to analyze the relationship between altered joint kinematics and long term cartilage health. Utilizing voxel based relaxometry with T_1p and T₂ mapping sequences, in conjuction with MRI kinematics of the tibia and femur bone, allowed for the assessment of local cartilage matrix changes 2 years following ACL reconstruction. Notably, anterior translation of the tibia in the injured knee was associated with greater cartilage degeneration in the medial femoral and tibial cartilage.

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