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Abstract #0662

3D MR Elastograpy in Prediction of Tumor Capsule Formation of Hepatocellular Carcinoma (HCC) in Patients with Hepatitis B Virus Infection

Jin Wang1, Hao Yang1, Yong Liu2, Jingbiao Chen1, Tianhui Zhang1, Kevin J. Glaser3, Xin Li4, Jun Chen3, Yao Zhang1, Qungang Shan1, Bingjun He1, Zhuang Kang1, Yin Meng3, Dzyubak Bogdan3, Venkatesh SK3, Ronghua Yan1, Xi Long1, and Richard L. Ehman3

1Department of Radiology, the Third Affiliated Hospital, Sun Yat-sen University (SYSU), Guangzhou, People's Republic of China, 2Department of Pathology, the Third Affiliated Hospital, Sun Yat-sen University (SYSU), Guangzhou, People's Republic of China, 3Department of Radiology, Mayo Clinic, Rochester, United States, 4GE Healthcare MR Research China, Guangzhou, People's Republic of China

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths around the world. Tumor capsule formation is a significant and independent predictor of survival and recurrence. We explored the potential value of HCC stiffness using 3D MR elastograpy for the prediction of tumor capsule formation. Results in 50 examinations showed that HCC stiffness has promise for the preoperative prediction of tumor capsule formation, thus providing motivation for further evaluation of HCC characteristics with MRE.

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