Abstract #0662

3D MR Elastograpy in Prediction of Tumor Capsule Formation of Hepatocellular Carcinoma (HCC) in Patients with Hepatitis B Virus Infection

Jin Wang¹, Hao Yang¹, Yong Liu², Jingbiao Chen¹, Tianhui Zhang¹, Kevin J. Glaser³, Xin Li⁴, Jun Chen³, Yao Zhang¹, Qungang Shan¹, Bingjun He¹, Zhuang Kang¹, Yin Meng³, Dzyubak Bogdan³, Venkatesh SK³, Ronghua Yan¹, Xi Long¹, and Richard L. Ehman³

¹Department of Radiology, the Third Affiliated Hospital, Sun Yat-sen University (SYSU), Guangzhou, People's Republic of China, ²Department of Pathology, the Third Affiliated Hospital, Sun Yat-sen University (SYSU), Guangzhou, People's Republic of China, ³Department of Radiology, Mayo Clinic, Rochester, United States, ⁴GE Healthcare MR Research China, Guangzhou, People's Republic of China

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths around the world. Tumor capsule formation is a significant and independent predictor of survival and recurrence. We explored the potential value of HCC stiffness using 3D MR elastograpy for the prediction of tumor capsule formation. Results in 50 examinations showed that HCC stiffness has promise for the preoperative prediction of tumor capsule formation, thus providing motivation for further evaluation of HCC characteristics with MRE.

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