Abstract #0668

A computer aided diagnosis (CAD) scoring tool: prostate cancer risk evaluation with PI-RADS v2 Guidelines

Lian Ding¹, Ge Gao², Yajing Zhang³, Chengyan Wang¹, Jue Zhang^1,4, Xiaoying Wang^1,2, and Jing Fang^1,4

¹Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, People's Republic of China, ²Department of Radiology, Peking University Frist Hospital, Beijing, People's Republic of China, ³Philips Healthcare, Suzhou, China, Beijing, People's Republic of China, ⁴College of Engineering, Peking University, Beijing, People's Republic of China

The second version of the Prostate Imaging Reporting and Data System (PIRADSv2) indicates the likelihood of a clinically significant cancer with a simplified 5-point scale. To assist radiologists in making diagnostic decisions consistent with the PIRADSv2, we proposed a machine learning-based computer aided diagnosis (CAD) scoring tool of prostate cancer risk evaluation by combining apparent diffusion coefficient (ADC) and T2-weighted MRI-based features. The tool could provide a malignancy prediction color map of 5 scores. The statistical results of the total score test for 130 patients between radiologist graded and the CAD tool showed high accuracy and AUC.

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