Abstract #0670

Comparing the Diagnostic Accuracy of Luminal Water Imaging with Diffusion-Weighted and Dynamic Contrast-Enhanced MRI for Evaluation of Prostate Cancer.

Shirin Sabouri¹, Silvia D Chang^2,3,4, Richard Savdie², Edward C Jones⁵, S. Larry Goldenberg^2,3, Peter C Black^2,3, and Piotr Kozlowski^2,3,4,6

¹Department of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada, ²Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada, ³Vancouver Prostate Centre, Vancouver, BC, Canada, ⁴Department of Radiology, University of British Columbia, Vancouver, BC, Canada, ⁵Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada, ⁶UBC MRI Research Center, Vancouver, BC, Canada

Luminal water imaging (LWI) is a newly developed MRI technique that has shown promising results for diagnosing and grading of prostate cancer. Incorporating LWI in clinical settings requires a profound investigation on its diagnostic accuracy by comparing it to existing clinical protocols. In this pilot study we have acquired and analyzed LWI, DWI, and DCE-MRI data from 15 patients to compare the diagnostic accuracy of LWI with the other two techniques. Our results show that LWI provides equal or higher accuracy in detection of tumors and better correlation with tumor grade compared to DWI and DCE-MRI.

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