Abstract #0678

Pseudo Continuous Arterial Spin Labeling Quantification Considerations in Hyperemic Cerebral Blood Flow

Adam Bush¹, Thomas Coates², and John Wood³

¹Biomedical Engineering/ Cardiology, University of Southern California/ Children's Hospital Los Angeles, Los Angeles, CA, United States, ²Hematology, Children's Hospital Los Angeles, Los Angeles, CA, United States, ³Cardiology, University of Southern California/ Children's Hospital Los Angeles, Los Angeles, CA, United States

In this work we compare 2D phase contrast (PC) and pseudo continuous arterial spin labeling (PCASL) estimates in subjects with hyperemic cerebral blood flow. We found that B1 ineffiency dependent reductions in labeling efficiency and venous outflow of ASL tracer in PCASL leads to underestimation of PC CBF estimates.

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