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Abstract #0677

Evaluation of Velocity Selective ASL Tagging Efficiency Utilizing Accelerated 3D Angiography

James H Holmes1, Tilman Schubert1, Prateek Sanan1, Patrick A Turski1, and Kevin M Johnson1,2

1Radiology, University of Wisconsin-Madison, Madison, WI, United States, 2Medical Physics, University of Wisconsin-Madison, Madison, WI, United States

Velocity Selective Arterial Spin Labeling (VS-ASL) has been suggested as a possible solution for evaluating perfusion and MRA in complex geometries without well-defined labeling planes as well as in cases of slow or complex flow patterns. The goal of this work is to assess the spatial distribution of VS-ASL tagging efficiency utilizing MR angiography. Specifically, we identify and characterize errors introduced by susceptibility induced magnetic gradients. In controlled phantom experiments and human subjects tagging efficiency demonstrated dependence both on the magnitude of susceptibility shift and the velocity of vessels flowing through those regions.

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