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Abstract #0718

Layer-specific analysis of cortical microstructure using in-vivo 7T diffusion MRI

Omer Faruk G├╝lban1, Federico De Martino1, An Thanh Vu2, Kamil Ugurbil3, Essa Yacoub3, and Christophe Lenglet3

1Department of Cognitive Neuroscience, Maastricht University, Maastricht, Netherlands, 2Center for Imaging of Neurodegenerative Diseases, Veterans Affairs Health Care System, San Francisco, CA, United States, 3Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States

We present unique in-vivo human 7T diffusion MRI data and a dedicated layer-specific analysis pipeline. We leverage the high spatial and angular resolution of this dataset to improve cortical fiber orientation mapping (i.e. limit gyral bias and identify fiber crossings), and study axonal trajectories within the cortex across depths.

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