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Abstract #0728

Human Hyperpolarized C-13 MRI Using a Novel Echo-Planar Imaging (EPI) Approach

Jeremy W Gordon1, Hsin-Yu Chen1, Peder EZ Larson1, Ilwoo Park1, Mark Van Criekinge1, Eugene Milshteyn1, Robert Bok1, Rahul Aggarwal2, Marcus Ferrone3, James B Slater1, John Kurhanewicz1, and Daniel B Vigneron1

1Radiology & Biomedical Imaging, UCSF, San Francisco, CA, United States, 2Medicine, UCSF, San Francisco, CA, United States, 3Clinical Pharmacy, UCSF, San Francisco, CA, United States

In this pilot study, we developed and applied a specialized symmetric EPI approach for the study of hyperpolarized [1-13C]pyruvate metabolism in the human prostate. We show that this approach can acquire ghost-free hyperpolarized [1-13C]pyruvate and [1-13C]lactate images with high spatiotemporal resolution in a clinical setting.

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