The separation of water and fat in zero echo time (ZTE) imaging is challenging for several reasons: First, echo-based signal models are violated for fast-relaxing spins and require the use of loud sequences. Second, frequency selective preparation pulses produce large SAR and are inefficient on short-T2 compounds. Finally the off-resonance induced phase vanishes at TE = 0. In this work, we introduce the principles of a technique that allows water-fat separation for a single ZTE acquisition and demonstrate it potential and limits with phantom and in-vitro experiments.
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