Abstract #0773

Suspicious Component Segmentation for Identifying Hippocampal Sclerosis Using Regularized Tissue-Fraction MR Fingerprinting

Kang Wang¹, Congyu Liao², Xiaozhi Cao², Zhixing Wang², Dengchang Wu¹, Hongjian He², Qiuping Ding², and Jianhui Zhong²

¹Department of Neurology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People's Republic of China, ²Center for Brain Imaging Science and Technology, Department of Biomedical Engineering, Zhejiang University, Hangzhou, People's Republic of China

A relaxometry-based tissue fraction segmentation using MR fingerprinting method was applied for identifying hippocampal sclerosis. The results demonstrated that tissue-fraction MR fingerprinting method could effectively segment multiple tissue components and mark the possible sclerosis regions, which is critical for clinical application including lesions diagnosis and multicomponent analysis.

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