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Abstract #0773

Suspicious Component Segmentation for Identifying Hippocampal Sclerosis Using Regularized Tissue-Fraction MR Fingerprinting

Kang Wang1, Congyu Liao2, Xiaozhi Cao2, Zhixing Wang2, Dengchang Wu1, Hongjian He2, Qiuping Ding2, and Jianhui Zhong2

1Department of Neurology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People's Republic of China, 2Center for Brain Imaging Science and Technology, Department of Biomedical Engineering, Zhejiang University, Hangzhou, People's Republic of China

A relaxometry-based tissue fraction segmentation using MR fingerprinting method was applied for identifying hippocampal sclerosis. The results demonstrated that tissue-fraction MR fingerprinting method could effectively segment multiple tissue components and mark the possible sclerosis regions, which is critical for clinical application including lesions diagnosis and multicomponent analysis.

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