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Abstract #0817

The comparative study of MR renography versus 99mTc-DTPA renal scintigraphy for determining split renal function of the transplanted kidney

Jing Wang1, Yang Fan2, and Yudong Zhang3

1Center for Medical Device Evaluation, CFDA, Beijing, People's Republic of China, 2MR Research China, GE Healthcare, Beijing, People's Republic of China, 3Department of Radiology, the First Affiliated Hospital with Nanjing Medical University, Nanjing, People's Republic of China

The evaluation of split kidney function is of clinical significance for patients after renal transplantation. This study explored two available approaches, dynamic MR renography vs. 99mTc-DTPA clearance, for determining split renal GFR in 57 transplanted patients. MR-based GFR was measured using an established Baumann-Rudin model, modified two-compartment and three-compartment model. MR results were compared with 99mTc-DTPA, using 24-h creatinine clearance rate as a reference. MRR using a 2C model had significantly higher accuracy (r = 0.925) than 99mTc-DTPA clearance (r = 0.317), thus could be a more promising way for evaluation of transplanted kidney function.

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