Abstract #0818

Initial experience with magnetic resonance elastography and acoustic radiation force impulse elastography in renal transplant patients

Paul Kennedy¹, Octavia Bane¹, Sonja Gordic¹, Cecilia Besa¹, Stefanie Hectors¹, Mathilde Wagner^1,2, Rafael Khaim³, Madhav Menon³, Vinay Nair³, Sara Lewis¹, and Bachir Taouli¹

¹Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ²Radiology, Groupe Hospitalier Pitié Salpêtrière, Paris, France, ³Recanati Miller Transplantation Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States

In this prospective study we compared renal transplant stiffness measured with MRE and ARFI ultrasound in 9 patients. Repeatability of both modalities was determined through test-retest imaging in 5 patients. MRE stiffness was significantly lower than ARFI stiffness as expected. MRE test-retest repeatability was excellent with mean coefficient of variation (CV) of 6%, while ARFI had CV of 30%. In addition, ARFI measurements exhibited a high inter-quartile range in the majority of cases suggesting inconsistency in the measurements. Our results suggest MRE is a more robust choice for renal transplant measurement compared to ARFI.

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