Dynamic contrast enhanced MRI can be used to obtain single-kidney GFR estimates but tradeoffs between spatial and temporal resolution lead to errors. We propose a novel reconstruction technique where AIFs are generated from images reconstructed with high temporal resolution while renal parenchyma signal is extracted from images reconstructed over a larger temporal window to generate images with high spatial resolution and improved image quality. We demonstrate the clinical validity of the method by estimating the GFR using our proposed method and compare it with serum creatinine based eGFR estimate.
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