Meeting Banner
Abstract #0904

Respiratory resolved, self-gated, 4-dimensional MRI using Rotating Cartesian K-Space (ROCK): technical validation and initial clinical experience on an MRI-guided radiation therapy system

Fei Han1, Ziwu Zhou1, Yu Gao1, Percy Lee2, Minsong Cao2, Daniel Low2, Ke Sheng2, Yingli Yang2, and Peng Hu1

1Radiology, University of California, Los Angeles, CA, United States, 2Radiation Oncology, University of California, Los Angeles, CA, United States

Respiratory revolved 4D-MRI is used to quantify patient-specific respiratory motion to ensure optimal dose delivery in the radiation therapy of abdominal tumors. In this work, we developed a 4D-MRI technique using 3D k-space encoding, respiratory motion self-gating, and compressive sensing image reconstruction. The proposed 4D-MRI technique could provide high resolution, high quality, respiratory motion resolved 4D images with good soft-tissue contrast and are free of the “stitching” artifacts usually seen on 4D-CT, which is the current clinical standard. Results from motion phantom, healthy volunteers in a 1.5T diagnostic scanner and liver cancer patient in a 0.35T MRI-guided radiation therapy system demonstrated the feasibility of using the proposed 4D-MRI in radiation treatment planning.

This abstract and the presentation materials are available to members only; a login is required.

Join Here