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Abstract #0906

Comparison of Spin-Echo Echoplanar Imaging and Gradient Recalled Echo Magnetic Resonance Elastography Pulse Sequences Among Patients with Hepatic Iron Overload at 3.0 T

Ely R Felker1, Steven S Raman1, Bradley D Bolster2, Holden Wu1, Kyung Sung1, Stephan Kannengiesser2, Brenda J Brown1, and David S Lu1

1Radiology, UCLA, Los Angeles, CA, United States, 2Siemens Healthcare

Most technical failures of GRE-based MR elastography are related to iron overload, especially at 3.0 T. SE-EPI-based MR elastography may be a useful alternative. 3.0 T GRE and SE-EPI MR elastography sequences were compared in 20 patients with iron overload (mean R2* 114 sec-1) in terms of quantitative liver stiffness (LS) and image quality score (IQS), based on wave propagation and confidence mask coverage, as determined by two experienced radiologists. LS measurements were not significantly different between the two sequences. SE-EPI showed a trend toward higher confidence mask coverage and significantly higher IQS for both readers compared to GRE.

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