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Abstract #0908

Treatment response of hepatic and renal stiffness in patients with chronic HCV infection monitored by multifrequency MR elastography

Jing Guo1, Stephan Marticorena Garcia 1, Florian Dittmann1, Thomas Fischer1, Jürgen Braun2, and Ingolf Sack1

1Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany, 2Department of Medical Informatics, Charité - Universitätsmedizin Berlin, Berlin, Germany

Multifrequency abdominal MRE was applied to monitor stiffness of the liver and kidney in renal transplant recipients with chronic HCV infection after antiviral therapy. Within a 6-months period after medication, hepatic stiffness was significantly reduced while renal stiffness in kidney transplants was not altered. Wave speed obtained by high-resolution multifrequency MRE can serve as a quantitative imaging maker to assess the treatment response and monitor abdominal organ stiffness longitudinally.

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