Abstract #0920

Anthropomorphic Spinal Cord Phantom with Induced Field Inhomogeneity

Alan C Seifert^1,2,3, Vaishali Patel¹, Merin Grace¹, Robin Li¹, Mohammad Molla⁴, Joseph Borrello^1,2,3, and Junqian Xu^1,2,3,5

¹Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ²Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ³Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ⁴Department of Mechanical Engineering, The City College of New York, New York, NY, United States, ⁵Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, United States

The human spinal cord exists in a particularly unfavorable magnetic field environment. Technical development of diffusion and functional MRI methods would be facilitated by a phantom to model spatially and temporally periodic field inhomogeneities. We have designed a phantom capable of simulating these specific field disturbances. The spinal canal was machined from acrylic, and the cord was cast of polyvinyl alcohol. The phantom was imaged using anatomical CT and MRI, and functional and diffusion EPI protocols. The phantom has relaxation and diffusion properties similar to the human cord, and air-filled vials create spatially periodic frequency shifts of -100 Hz.

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