Abstract #0922

Quantification of Increased Myocardial Stiffness in Patients with Hypertrophic Cardiomyopathy Using 3D High Frequency Cardiac Magnetic Resonance Elastography

Shivaram Poigai Arunachalam¹, Arvin Arani¹, Ian Chang², Yi Sui¹, Phillip Rossman¹, Kevin Glaser¹, Joshua Trzasko¹, Kiaran McGee¹, Armando Manduca³, Richard Ehman¹, Richard Ehman¹, and Philip Araoz¹

¹Radiology, Mayo Clinic, ROCHESTER, MN, United States, ²Cardiovascular Diseases, Mayo Clinic, ROCHESTER, MN, United States, ³Biomedical Engineering and Physiology, Mayo Clinic, ROCHESTER, MN, United States

Abnormal thickening of myocardium in patients with hypertrophic cardiomyopathy impairs the pump function, and in particular affects diastolic filling with a known increase in myocardial stiffness. The purpose of this work was to determine if 3D high frequency cardiac MR elastography (MRE) can quantitatively differentiate increased myocardial stiffness in HCM patients compared to healthy volunteers. 36 patients with clinical diagnosis for hypertrophic cardiomyopathy (HCM) and 47 healthy volunteers were studied. The myocardial stiffness of HCM patients (mean: 12.01 kPa) was found to be significantly stiffer (p < 0.01) than healthy controls (mean: 7.79 kPa).

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.