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Abstract #0924

4D Flow MRI, Cardiac Function, and Myocardial T1-Mapping: Ventricular-arterial coupling in Patients with Bicuspid Aortic Valve (BAV)

Julia Geiger1, Amir Rahsepar1, Kenichiro Suwa1, Alex Powell1, Alex J Barker1, Jeremy D Collins1, James Carr1, and Michael Markl1,2

1Radiology, Northwestern University, Chicago, IL, United States, 2Biomedical Engineering, Northwestern University, Chicago, IL, United States

BAV is the most prevalent congenital cardiovascular malformation. Its association with progressive ascending aortic dilatation and concomitant aortic valve stenosis or regurgitation with increasing age has a critical impact on patients’ morbidity. We applied a comprehensive CMR protocol in 50 BAV patients consisting of cine-imaging, T1-mapping and 4D flow MRI to simultaneously assess cardiac parameters and aortic hemodynamics. We observed significant relationships between LV mass and WSS as well as peak velocities in the AAo and arch, likewise in the sub-cohort with normal valve function, leading us to the hypothesis that there is proof for ventricular-aortic coupling in BAV patients.

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