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Abstract #0977

High resolution imaging of the optic chiasm at 7T MRI improves lesion detection and tumour delineation compared to 3T

Guido van Haren1, Lorna Grech-Fonk2,3, Marco Verstegen4, Wouter Teeuwisse2, Teresa Ferreira1, Irene Notting3, Wouter van Furth4, Alberto Pereira5, Gregorius Luyten3, Andrew Webb2, and Jan-Willem Beenakker2,3

1Radiology, LUMC, Leiden, Netherlands, 2Radiology, CJ Gorter center for high field MRI, LUMC, Leiden, Netherlands, 3Ophthalmology, LUMC, Leiden, Netherlands, 4Neurosurgery, LUMC, Leiden, Netherlands, 5Endocrinology, LUMC, Leiden, Netherlands

The limited resolution of 3Tesla MRI often leads to missed lesions or ambiguities in the tumour environment for patients with a pituitary macro-adenoma. In this study we developed a robust high-resolution 7Tesla MRI-protocol of the optico-chiasmatic system and evaluated its clinical value. The 7T MR-images reveal tiny lesions in the optic nerve or chiasm which are not visible at 3T. These lesions could explain the vision loss for 3 of the 7 evaluated patients and gave the physician new treatment possibilities. Overall, this study shows the great clinical opportunities of 7Tesla MRI for patients with pituitary macro-adenoma or other neuro-ophthalmic conditions.

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