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Abstract #0982

3D printed Breast DCE-MRI phantom to mimic structure and pharmacokinetics

Nithin N Vajuvalli1, Chethan Kumar M1, Amaresha Shridhar Konar1,2, Shivaprasad Ashok Chikop1, Darshan Shivaramu Keelara1, Ashwini Kumnoor1, Ramesh Venkatesan2, and Sairam Geethanath1

1Medical Imaging Research Centre, Dayananda Sagar Institution, Bangalore, India, 2Wipro GE healthcare, Bangalore, India

DCE MRI plays a critical role in routine clinical breast examination. Current work focuses on the development of Breast DCE MRI phantom using a 3D printer to mimic poor and well perfused regions. The phantom developed was controlled through user entered Ktrans values entered in a GUI which interfaced with a peristaltic pump to control flow rates. The Kep parameters was controlled through the 3D model geometry. Prospective MR images of the phantom were acquired on a 1.5T scanner using the TRICKS sequence; and pharmacokinetic maps based on Tofts model were computed and quantified.

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