Abstract #1014

Effects of 5 alpha-Reductase Inhibitors on Detection of Prostate Cancer on MRI

Lori Mankowski Gettle¹, Shivashankar Damodaran ², David F. Jarrard², and Frederick Kelcz¹

¹Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States, ²Urology, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States

5 alpha reductase inhibitors have shown promise in increasing the detection of prostate cancer in prior ultrasound studies. No studies have been performed looking at the effect of 5 alpha reductase inhibitors on increasing the conspicuity of prostate cancer in MRI. The purpose of this study was to determine if treatment with a 5 alpha reductace inhibitor could increase sensitivity for the detection of prostate cancer in the background setting of benign prostatic hypertrophy.

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