Meeting Banner
Abstract #1015

Improved Accuracy of Apparent Diffusion Coefficient (ADC) Quantification: Evaluation in Prostate Diffusion Imaging without Using Endorectal Coils

Xiaodong Zhong1,2, Marcel D. Nickel3, Stephan A.R. Kannengiesser3, Alto Stemmer3, Brian M. Dale4, Berthold Kiefer3, and Mustafa R. Bashir5

1MR R&D Collaborations, Siemens Healthcare, Atlanta, GA, United States, 2Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, United States, 3MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany, 4MR R&D Collaborations, Siemens Healthcare, Cary, NC, United States, 5Center for Advanced Magnetic Resonance Development, Duke University Medical Center, Durham, NC, United States

In prostate DWI, low SNR often causes inaccuracy in ADC quantification if not compensated, especially when using surface array coils. Endorectal coils can be used, although associated with substantial setup time, patient discomfort and complications. In this work, a noise bias correction framework was developed and validated in a Monte Carlo simulation, a diffusion phantom, and 14 prostate imaging subjects. Using data acquired with an endorectal coil as a reference, this framework showed improved accuracy of ADC quantification in the prostate when only non-endorectal coils were used. This framework may allow quantitative prostate diffusion imaging without requiring endorectal coils.

This abstract and the presentation materials are available to members only; a login is required.

Join Here