Abstract #1026

Respiratory Motion Compensation in the Liver using Fat-Only Self Gated Signal

Thomas Martin^1,2, Tess Armstrong^1,2, Ely Felker², James Sayre², Steve Raman², Holden Wu², and Kyunghyun Sung²

¹Biomedical Physics, University of California, Los Angeles, Los Angeles, CA, United States, ²Radiological Sciences, University of California, Los Angeles, Los Angeles, CA, United States

A multi-echo 3D golden angle radial gradient echo (GRE) sequence for fat-only respiratory motion extraction is a promising technique for liver dynamic contrast enhancement MRI (DCE-MRI), because it has inherent motion robustness, while providing other advantages, such as water-only images and R₂* mapping. In this work we demonstrate that respiratory motion correction in the liver can be achieved using a fat-only self-navigated signal with minimal error in the fat-water separation (< 5%). Using this technique has implications of a more robust motion correction for liver DCE-MRI due to its inherent separation between respiratory motion signal and contrast uptake.

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