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Abstract #1076

Inflammatory activity of Crohn's disease: Evaluation by MR T2*mapping without intravenous enhancement

Si yun Huang1, Xue hua Li1, Zhong wei Zhang2, Jin jiang Lin1, Li Huang1, Zhuang nian Fang1, Meng chen Zhang1, Meng jie Jiang3, Hua song Cai1, Margaret H. Pui4, Shi ting Feng1, Can hui Sun3, and Zi ping Li3

1Department of Radiology, The First Affiliated Hospital of Sun Yat-Sen University´╝îGuangzhou, China, Guangzhou, People's Republic of China, 2Department of Biomedical Engineering, Cancer Biology and Radiology, Wake Forest School of Medicine, 3Department of Radiology, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Stomatology, 4Department of Radiology, Conde de S. Januario Central Hospital, Macau

Crohn's disease (CD) is a chronic relapsing inflammatory bowel disease leading to structurally irreversible bowel damage. The incidence of CD had been increasing in the past century epidemiologically . Accurate evaluation of CD activity is crucial for new therapeutic goals of mucosal healing, preventing bowel damage, limiting disability, and improving quality of life . Although colonoscopy remains the gold standard for assessing CD activity, it is invasive, limited to assessment of the small bowel, and not suitable for continuing monitoring of CD activity . Thus, seeking for alternative noninvasive and accurate approaches to assess CD activity is necessary.

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