This study introduces a single-shot 3D EPI sequence for rapid motion field acquisition. The method can be applied for MRE under pulsatile motion or for directly analyzing intrinsic motion fields in pulsatile organs such as the brain. Through 3D k-space sampling, inter-slice phase offset artifacts, which essentially result from 2D k-space MRE, are most effectively avoided. In a first application we used the new method for the measurement of intrinsic brain pulsation in the human brain and analyzed the intensity of deflection field components by stochastic sampling at rest and during Valsalva maneuver.
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