Abstract #1134

Preoperative assessment of tumor stiffness and tumor-brain adhesion in patients with vestibular schwannoma using MR elastography-based method

Prateek Kalra¹, Arunark Kolipaka, PhD¹, Brian Raterman¹, Oliver Adunka, MD², Michael Harris, MD², and Daniel M. Prevedello, MD³

¹Department of Radiology, Ohio State University Wexner Medical Center, Columbus, OH, United States, ²Department of Otolaryngology, Ohio State University Wexner Medical Center, Columbus, OH, United States, ³Department of Neurological Surgery, Ohio State University Wexner Medical Center, Columbus, OH, United States

Microsurgery in vestibular schwannoma patients aims to complete tumor resection without compromising any neurological functionality. Inadequate preoperative knowledge of tumor may prolong surgical time and increase risk of postoperative complications. Previous studies have used magnetic resonance elastography (MRE) based method to determine tumor stiffness and tumor-brain adhesion, separately. But none of the studies have investigated tumor stiffness and tumor-brain adhesion together. The aim of this study is to bring together the two MRE-based outcomes – tumor stiffness and tumor-brain adhesion – and correlate with surgical findings. Preliminary results show a good correlation between preoperative assessment of tumor and surgical findings.

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