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Abstract #1179

MRI-based myocardial ablation lesion extent relates to area of voltage reduction in MR-guided electroanatomical voltage maps

Philippa Krahn1,2, Venkat Ramanan2, Labonny Biswas2, Nicolas Yak2, Kevan Anderson2, Jennifer Barry2, Mihaela Pop1,2, and Graham A Wright1,2

1Medical Biophysics, University of Toronto, Toronto, ON, Canada, 2Sunnybrook Research Institute, Toronto, ON, Canada

In this study we investigated subtle features of acute RF ablation lesions using co-registered MR images and electroanatomic voltage maps (EAVM) acquired under MR guidance. Of particular interest was the relationship between the extent of edema detected in T2 maps and altered electrical activity surrounding the ablation site. The results from this study aim to elucidate mechanisms of high ventricular arrhythmia recurrence rates after successful RF ablation therapy, which may be driven by transient conduction block produced acutely by edema.

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