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Abstract #1178

A Combined Intravascular MRI Endoscope and Intravascular Ultrasound (IVUS) Transducer for High-Resolution Image-Guided Ablation

Xiaoyang Liu1,2, Nicholas Ellens1, Emery Williams3, Everette Clif Burdette3, Parag Karmarkar1, and Paul Bottomley1,2

1Russell H. Morgan Department of Radiology, Johns Hopkins University, Baltimore, MD, United States, 2Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD, United States, 3Acoustic MedSystems, Inc, Champaign, IL, United States

An intravascular MRI (IMRI) loopless antenna is combined for the first time with an intravascular water-cooled ultrasound ablation transducer as a possible tool for providing high-resolution MRI-guided ablations of pathological tissue via intravascular access. High resolution anatomical MRI, and real-time MRI thermometry were used to monitor ablation delivery in phantoms and tissue specimens. Results show that IMRI can guide IVUS-mediated directional ablation with minimal image artifacts. This permits the monitoring of thermal dose and therapy titration while minimizing potential thermal damage to the vessel wall.

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