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Abstract #1228

Quantifying Fat Mass and Energy Content in Brown Adipose Tissue

Jedrzej Burakiewicz1, Gustavo de Abreu Vieira2, Laura G.M. Janssen2, Kimberly J. Nahon2, Mariƫtte R. Boon2, Andrew G. Webb1, Hermien E. Kan1, and Patrick C.N. Rensen2

1Gorter Center for High Field MRI, Radiology, Leiden University Medical Centre, Leiden, Netherlands, 2Endocrinology, Leiden University Medical Centre, Leiden, Netherlands

MRI of Brown Adipose Tissue (BAT) is gaining popularity as an alternative to PET-CT. Most commonly used marker in quantifying BAT is fat fraction, however there is no consensus to the range of fat fractions separating BAT and WAT. In this work we show how calculating energy content and total fat mass allows to avoid partial volume effect and provides more quantitative markers than fat fraction. We also argue that the fat fractions in the high end of the range (80% - 100%) contribute significantly to BAT activity.

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