Abstract #1266

Tridimensional Axial and Circumferential WSS from 4D flow data using a finite element method and a Laplacian approach

Julio Sotelo^1,2, Jesús Urbina³, Bram Ruijsink⁴, David Nordsletten⁴, Joaquín Mura¹, Reza Razavi⁴, Daniel Hurtado⁵, and Sergio Uribe^1,3

¹Biomedical Imaging Center, Pontificia Universidad Católica de Chile, Santiago, Chile, ²Department of Electrical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, ³Department of Radiology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile, ⁴Department of Biomedical Engineering, King's College London, London, United Kingdom, ⁵Department of Structural and Geotechnical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile

The WSS and OSI play a critical role in the progression of different vascular diseases, the multidirectional nature of WSS, can alter the balance of the endothelial cells. But the multidirectional nature of WSS only has been analyzed in 2D section. In this work, we propose a new method based on 3D finite-element and a Laplacian approach to decompose the WSS vector in an axial (WSS_A) and circumferential (WSS_C) component in a 3D domain. The 3D method provides an excellent agreement of the quantification of WSS_A and WSS_C in comparison with the actual 2D method.

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