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Abstract #1358

Proton Density Mapping and Receiver Bias Correction for Absolute Quantification with MR Fingerprinting

Anagha Deshmane1, Debra McGivney2, Yun Jiang1, Dan Ma2, and Mark Griswold2

1Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, 2Radiology, Case Western Reserve University, Cleveland, OH, United States

MR Fingerprinting (MRF) can simultaneously map multiple parameters and can be used to compute estimates of tissue fractions. However, MRF-derived M0 maps contain information about both proton density (PD) and the receiver sensitivity profile (RP). Here we estimate relative PD and RP from MRF M0 and T1 maps. Relative PD and tissue fractions are combined for absolute quantity mapping of CSF, gray matter, and white matter as a fraction of the voxel equilibrium magnetization.

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