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Abstract #1359

In vivo MR blood oximetry based on $$$T_2$$$-prepared bSSFP

Michael C Langham1, Ana E Rodríguez-Soto1, Hyunyeol Lee1, Nadav Schwartz2, and Felix W Wehrli1

1Radiology, University of Pennsylvania, Philadelphia, PA, United States, 2Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA, United States

To develop in vivo MR oximetry based on T2-prepared bSSFP constant refocusing-pulse interval ($$$\tau_{180}$$$) T2-preparation, three-parameter signal fitting for T2 extraction and magnetization reset for shortened pulse sequence cycle were implemented and evaluated against a multi-spin echo sequence using static and flowing MnCl2 solutions with known T2 values. The whole-blood T2 was also quantified to investigate the effect of varying . The phantom results support three-parameter fitting, and <5% error incurred in T2 quantification with shortened T2-preparation cycle and presence of constant flow. Approximately 10% longer whole-blood T2 was observed with constant relative to varying .

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