T1rho is often measured by constant amplitude spin-lock, which can be played out either on-resonance or off-resonance. A major challenge to T1rho imaging with constant amplitude spin-lock is its susceptibility to B1 RF and B0 field inhomogeneity. A method to improve the robustness of on- and off-resonance constant amplitude spin-lock is presented in this work. The experimental results indicated that the proposed method can achieve superior image quality and improved quantification accuracy compared to the conventional approach in the presence of system imperfections.
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