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Abstract #1395

Correct Shaking Artifact in Diffusion Spectrum Imaging Using Estimated Maximum Likelihood

Chang-Le Chen1, Yu-Jen Chen2, Yung-Chin Hsu2, and Wen-Yih Isaac Tseng1,2,3

1Graduate Institute of Brain and Mind Sciences, National Taiwan University College of Medicine, Taipei, Taiwan, 2Institute of Medical Device and Image, National Taiwan University College of Medicine, Taipei, Taiwan, 3Molecular Imaging Center, National Taiwan University College of Medicine, Taipei, Taiwan

Unexpected phase errors occurred in the k-space of the diffusion spectrum EPI sequence would lead to abrupt shifts in the phase-encoding direction across different diffusion gradient directions which cause shaking artifact of the image. The shaking artifact can lead to errors in image registration and diffusion index calculation. Here, we developed an estimated maximum likelihood method to detect and correct image shifts. After correcting the shaking artifact, the performance of registration and the diffusion index calculation were significantly improved comparing to the images without correction.

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